"The automated cultivation system is an extremely innovative system. The integration of different technologies makes it possible to solve typical problems associated with the use of equipment currently on the market, such as the use of bulky and highly specific devices and interfaces, the absence of a disposable cultivation element, the low level of parallelization of the process and the complexity of assembling the units. The use of miniaturized precision valves and a pulsation-free pump is critical to avoid high mechanical stress on the cell cultures, which could interfere with their growth. The miniaturized fluid handling system developed in this study will thus allow much gentler and more realistic growth conditions than before."